The Vienna Biocenter in the third district of Vienna has established itself as the premier location for life sciences in Central Europe and is a world-leading international bio-medical research center.

 

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Welcome to the Vienna Biocenter Core Facilities

Facilities:
  • Advanced Microscopy
    High resolution optical imaging and spectroscopy techniques / Microscope customization and development.
  • Bioinformatics & Scientific Computing
    We provide unique expertise and services in the areas of bioinformatics and scientific computing to academic and industrial researchers.
  • Electron Microscopy
    To see what no one has seen before!
  • HistoPathology
    We provide expertise and resources for a wide range of histological and pathological studies in mice and a number of other organisms.
  • Empowering your research - get quantitative data on the building blocks of life!
  • Next Generation Sequencing
    Genomics’ most flexible and powerful tool.
  • Plant Sciences
    ... take your plant research to the next level!
  • Preclinical Phenotyping
    State-of-the-art of phenotypic screening of Mouse Behavior, Metabolism & Physiology.
  • Preclinical Imaging
    Ultra high 15.2 T Bruker MR imaging.
  • Protein Technologies
    We provide expertise in recombinant protein technologies and genome engineering.
  • Vienna Drosophila Resource Center
    Drosophila resources for researchers worldwide.
  • Child Care Center
    The Child Care Center hosts not only little researchers from the Vienna Biocenter but also young media kids from the Media Quarter Marx.

Grants/Projects

Novel Magnetic Nanostructures for Medical Applications (MAGNAMED)

The Horizon 2020 sub-programme MCSA RISE provides support of R&D activities by means of targeted staff exchanges of the partnering organisations. The 14 partners of the project MAGNAMED will exchange their knowledge and expertise in various aspects of bio-imaging methods, which will bring the newest trends in this field to VBCF.

FemTECH Praktika for Female students 2016

13 summer/autumn fellowships of female students with the aim of initiating their scientific career. Their main goal is to work on further improvement of our services.

Brillouin Light Scattering Microspectroscopy for Biology and Biomedical Research & Applications (BioBrillouin)

The new COST Action aims at bringing together experts on Brillouin Light Scattering Spectroscopy and establishing a network which will be able to bring this novel technique to the field of life sciences and biomedicine.

Creating synergies between research infrastructures to stimulate innovation in the cross-border region

The project focuses on research infrastructures (RI) in the field of bio- and nanotechnology whose supportive role in both basic and applied science has become an indispensable part of scientific research. The main goal of the project is to prepare and validate a sustainable model of cross-border collaboration (Austria – Czech Republic) of RI that will ensure 1) effective exploitation of complementary equipment and expertise, 2) accessibility and promotion of the cross-border RI for regional users, both academic and industrial.

“I first came to the VBC in 2006 with the intention of staying only three or four years. Nine years later I am still here - the campus just keeps getting better!”

Peggy Stolt-Bergner, Protein Technologies

“VBC - where top expertise and cutting edge scientific infrastructure meets outstanding research and a great atmosphere.”

Jakub Jez, Plant Sciences Facility Head

“The Campus VBC is probably the most vibrant research site in Austria, so anyone interested in research would want to be here.”

Kareem Elsayad, Core Facility Head

“VBCF provides state-of-the-art equipment and dedicated experts. We help you to push your research further.”

Sylvia Badurek, Core Facility Head at Preclinical Phenotyping Facility

Who We Are

The Vienna BioCenter Core Facilities GmbH (VBCF) is a publicly funded non-profit research institute, situated at the Vienna Biocenter.

We offer access to state-of-the-art research infrastructure and scientific services. Our customers are academic research institutions and companies in the field of Life Sciences.

VBCF is open to all forms of scientific collaborations.

 

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Horizon 2020 collaboration offer

VBCF Newsletter

 

 

We offer cutting edge infrastructure and scientific services to enable our customers to compete at the forefront of science.

Passion for technology and science, continuous training and lifelong learning are what make VBCF staff the highly qualified experts we need to develop and operate our scientific infrastructure to the satisfaction of our customers.

We constantly scout for new and emerging technologies that can better address the research questions of our customers and aim for joint exploration.

We contribute to the most effective and efficient usage of public and private research funds by providing high-quality service and economies of scale through centralization.

VBCF acts as a communication platform and a joint repository of expertise. Technical knowledge and skills are preserved when researchers leave the Vienna Biocenter and are forwarded to the next generation of researchers.

We cooperate with other providers of research infrastructure to make technologies beyond our own portfolio accessible and to improve the quality of our services through benchmarking.

About VBCF

The Vienna Biocenter Core Facilities GmbH (VBCF) is a publicly funded non-profit research institute, situated at the Vienna Biocenter.  VBCF was founded in 2010 as a limited liability company (GmbH) according to Austrian law. VBCF’s stakeholders are:

The operation of VBCF is funded by the Federal Ministry of Science, Research and Economy (bm.wfw) and the City of Vienna, by fees charged for delivered services and by additional research grants.

VBCF operates 11 scientific core facilities and the shared Child Care Center of the Vienna Biocenter as shown in the organization chart below.

Management

Andreas Tiran
Managing Director

Andreas Tiran took up his appointment as Managing Director of the VBCF in January 2011. He has extensive previous experience both as a researcher as well as a manager of scientific infrastructure.

since 2011 Managing Director of Vienna Biocenter Core Facilities GmbH (VBCF), Vienna Biocenter, Austria
2004-2010 Director of the Center for Medical Research (ZMF), Medical University of Graz, Austria
2001-2004 Department Head at the Clinical Institute of Medical and Chemical Laboratory Diagnostics, University of Graz, Austria
2001 Associate Professor of Laboratory Medicine, University of Graz, Austria
1996-2001 Senior physician, deputy head, Department of Laboratory Medicine, University of Graz, Austria
1995 Board Certification Medical and Chemical Laboratory Diagnostic
1994-1996 Postdoc at the Department of Clinical Immunology, University Hospital of Groningen, The Netherlands
1989-1994 Resident at the Department of Internal Medicine, University of Graz, Austria
1982-1988 School of Medicine, University of Graz

Go to the full CV of Andreas Tiran.

Contact:
phone: +43 1 796 23 24 7010
mail: andreas.tiran@@vbcf.ac.at
or
Barbara Miksch (Assistant to Managing Director)
phone: +43 1 796 23 24 7000
mail: barbara.miksch@@vbcf.ac.at

Peggy Stolt-Bergner
Authorized Representative of VBCF

Peggy Stolt-Bergner is Deputy Director and supports the Managing Director in the running of the institute.

since 2014 Authorized Representative of VBCF
since 2011 Head of VBCF Protein Technologies Facility
2006-2011 IMP Fellow, Research Institute of Molecular Pathology
2004-2006 Postdoctoral Fellow, Max Planck Institute of Biophysics,
1999-2004 PhD, Biochemistry and Molecular Pharmacology, Harvard Medical School

Go to the full CV of Peggy Stolt-Bergner

Contact:
phone: +43 1 796 23 24 7070
mail: peggy.stolt@@csf.ac.at

Administration

Barbara Miksch started at the VBCF from the very beginning in 2011 and is responsible for office administration, personnel administration and also external communications. 

phone: +43 1 796 23 24 7000
mail: barbara.miksch@vbcf.ac.at

Anastasia Manina joined the VBCF Administration in October 2014 as a controller. Her former international work experience is the perfect prerequisite for looking after the VBCF budget. 

phone: +43 1 796 23 24 7011
mail: anastasia.manina@@vbcf.ac.at

Judith Utner is supporting the Administration, she’s responsible for incoming and outgoing invoices and all other daily business.

phone: +43 1 796 23 24 7012
mail: judith.utner@@vbcf.ac.at

 

 

Lada Fialova joined VBCF in March 2015 as grant manager. Her responsibility is to support and facilitate search for grant opportunities, grant applications, and grant management.

phone: +43 1 796 23 24 7013
mail: lada.fialova@vbcf.ac.at

 

 

Strategic Information Management

The Strategic Information Management (SIM) facility is responsible for a common VBCF IT strategy and centralizes the most important IT tasks of the VBCF. The goal of this facility is to concentrate, merge and plan all IT requirements of the VBVF and setup a service oriented architecture which facilitates the flow of information between the VBCF facilities and administration.

Thomas Micheler is head of Strategic Information Management (SIM) facility since summer 2013. He is responsible for a comprehensive IT strategy and IT controlling for the VBCF.

phone: +43 1 796 23 24 7023
mail: thomas.micheler@@vbcf.ac.at

Jan Sladek joined the Strategic Information Management (SIM) facility as software engineer in November 2013. He analyzes IT related requirements and develops/maintains VBCF wide information systems.

phone: +43 1 796 23 24 7228
mail: jan.sladek@@vbcf.ac.at

Institutional Collaborations

VBCF has institutional collaborations with national and international research institutions, universities and other organizations with the following goals:

  • Initiation of joint research projects
  • Facilitation of staff exchange and development of joint training programs
  • Improved access to cutting-edge technologies through resource sharing

Core For Life

Core for Life is an excellence initiative of six leading European core facility organizations. The common intention of the members of Core For Life is to collaborate in organizational and operational aspects of core facility management and scientific support of life science research. The Core For Life alliance envisions exploring and using the potential of bundling core facility expertise across institutions and countries.

Website: www.coreforlife.eu
Interview: Nature Med. 2013, 19, 802

NGS-Platform in Vienna

Next-generation sequencing technology is rapidly evolving and transforming both basic biological science and biomedicine. In order to remain competitive, research organizations in Vienna need to actively invest in this technology. The main goal of the proposed Joint Technology Platform for Next Generation Sequencing in Vienna is to avoid unnecessary overlaps and invest into the newest NGS technologies and equipment in a coordinated and cost-efficient way.

MRI-Platform in Vienna

Since 2013 the VBCF, the AIT Austrian Institute of Technology, the University of Veterinary Medicine and the Medical University of Vienna are collaborating to create a translational research platform for preclinical MRI imaging with the best technical, financial and scientific solutions. Through the collaboration of the most experienced scientific institutions in preclinical imaging in the area of Vienna, we aim to intensify MR research and explore the potential of synergetic effects.

EuroBioImaging

Cutting-edge and innovative imaging technologies are revolutionizing the life sciences. Recent developments enable scientists to visualize and thereby better understand the processes that govern life and disease in cells and organisms. Euro-BioImaging is a research infrastructure project of the ESFRI Roadmap. It aims at creating a pan-European network of advanced imaging facilities that provide open access to advanced imaging technology for all European life scientists. The current VBCF initiative aims at the establishment of a EuroBioImaging node in Vienna by joining forces with universities and other research institutions.

New platform for future integration into EuroBioImaging created, read more here.

IST-A

Both VBCF and ISTA, the Institute of Science and Technology Austria, have committed themselves to coordinate the purchase of expensive instruments, to increase capacity usage and to bundle core facility expertise across the institutions. In particular VBCF and ISTA will join forces in providing access to state-of-the-art electron microscopy to their research groups.

AGES

In 2012, VBCF established a collaboration with AGES, the Austrian Agency for Health and Food Safety. Both institutions operate large-scale plant growth facilities with complementary technical specifications. The goal of the collaboration is the realization of research and development projects in life science by mutual use of technical scientific infrastructure, personnel, know-how, and operating resources.

CEITEC

CEITEC is a scientific centre in the fields of life sciences, advanced materials and technologies whose aim is to establish itself as a recognized centre for basic as well as applied research. CEITEC offers a state-of-the-art infrastructure and great conditions to employ excellent researchers. It is a consortium whose partners include the most prominent universities and research institutes in Brno, Czech Republic: Masaryk University, Brno University of Technology, Mendel University in Brno, University of Veterinary and Pharmaceutical Sciences in Brno, Veterinary Research Institute and Institute of Physics of Materials of the Academy of Sciences of the Czech Republic. CEITEC works closely with the Region of South Moravia and the City of Brno to help increase local innovative capacity.

Basic overview: 6 partners, 7 research programs, 61 research groups, 557 researchers (2015), 25.000 m2 of new laboratories, 10 core facilities

website: http://www.ceitec.eu/core-facility/list/

Career

Contact

E-Mail: contact@@vbcf.ac.at

Phone: +43 1 796 23 24 7000

Metabolomics (METABOL)

Introduction

Biological research in the post-genomic era has become largely dependent on technologies allowing the large scale analysis of biological systems and processes. One of these approaches, metabolomics, aims for the comprehensive and quantitative analysis of small biomolecules such as sugars, lipids or nucleic acids in biological samples. Together with genomics and proteomics, this emerging technology will allow to obtain a global view on biological systems and processes. The goal of the Metabolomics Facility is to deliver state-of-the-art quantitative and qualitative analysis of small organic compounds to users’ groups form both academia and industry. This task is provided by employing diverse methodologies based on liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). 

Services 

The facility will offer targeted analysis of user-defined compounds by targeted LC-MS/MS, including the respective methods development. In addition, we will offer several panels of already characterized targets to assess changes in various biochemical pathways. This approach can be used for exploratory studies and will be extended in the future to untargeted analysis of samples.

Contact 

Thomas Köcher
Head of Metabolomics Facility (METABOL)

Vienna Biocenter Core Facilities GmbH 
Dr. Bohr-Gasse 3, 1030 Vienna
+43-1-79044 - 4283
thomas.koecher@@vbcf.ac.at
www.vbcf.ac.at/metabol

Novel magnetic nanostructures for medical applications (MAGNAMED)

Duration: 4 years

Funded by: EU

Programme: Horizon 2020

Sub-programme: Marie Skłodowska-Curie Actions, Research & Innovation Staff Exchanges

Partners:

·         UNIVERSIDAD DEL PAIS VASCO, Spain (coordinator),

·         IMG PHARMA BIOTECH SL, Spain

·         Nanovex Biotechnologies SL, Spain

·         UNIVERSIDAD COMPLUTENSE DE MADRID, Spain

·         INESC MICROSISTEMAS E NANOTECNOLGIAS-INSTITUTO DE ENGENHARIA DE SISTEMAS DE COMPUTADORES PARA OS MICROSISTEMAS E AS NANOTECNOLOGIAS, Portugal

·         UNIVERSIDADE DO PORTO, Portugal

·         GEBZE TECHNICAL UNIVERSITY (Turkey)

·         VIENNA BIOCENTER CORE FACILITES GMBH (Austria)

·         COMISSAO NACIONAL DE ENERGIA NUCLEAR- CENTRO DE DESENVOLVIMENTO DA TECNOLOGIA NUCLEAR (Brazil)

·         THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (USA)

·         The University of Texas at San Antonio (USA)

·         CEDENNA (Chile)

·         UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (Chile)

·         ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO (Portugal)

·         UNIVERSIDADE ESTADUAL DE CAMPINAS (Brazil)

 

Total project costs: 846.000 EUR

Project summary:

MAGNAMED designs, fabricates, and assesses novel magnetic nanostructures (MNS) with unique spin configurations for innovative diagnostics and therapy techniques. An early stage detection and an effective treatment are keystones to reduce cancer mortality. Current clinical procedures fail to detect small concentration of tumoral biomarkers. Magnetic nanoparticles (MNP), like beads, have attracted much attention for their capability to improve cancer detection limits and treatment technologies. However, there are several limitations to the use of MNP. As an emerging alternative, MNS are being explored. Unlike MNP, MNS (e.g. nanodisks) present a planar shape with novel properties for diagnosis: high magnetic moment and large size, which can significantly improve the sensor sensitivity, and for therapy: due to their planar shape, alternate magnetic fields provoke a magneto-mechanical action on the cell membrane that triggers cell death. The efficiency of MNS in these two medical applications has not been investigated yet for MNS at the nanometer scale.

The challenge of this project is to produce MNS with nanometer dimensions suitable for medical applications. Several lithography techniques will be used to fabricate MNS in vortex and antiferromagnetic spin configurations covering a broad size range (40 to 4000 nm). After functionalization, MNS will be exploited in:

(i)                  Diagnostics, using giant magnetoresistance (GMR) sensors for the detection of tumoral biomarkers (dermicidin and carcinoembryonic antigen), and

(ii)                Therapy, effectiveness of tumoral cell annihilation by the magneto-mechanical action of MNS will be evaluated in vitro assays of melanoma and colorectal cancer cells.

MAGNAMED is a cross-sectoral and interdisciplinary project involving Physics, Chemistry and Medicine. Findings will have a medium-term impact on the European strategy for early stage detection of cancer and a long-term impact on the development of novel and groundbreaking therapeutics techniques.

Brillouin Light Scattering Microspectroscopy for Biology and Biomedical Research & Applications

Contact: Kareem Elsayad, Head of CF Advanced Microscopy, +43 1 796 2324 7110

 

Duration: March 2017 – February 2021

 

Partners: VBCF (Action main Proposer), 28 other proposers from 11 countries

 

Funded by: EU

 

Programme: COST

 

Total project costs: ca 130.000 EUR/year

 

Project summary:

The action “Brillouin Light Scattering Microspectroscopy for Biological and Biomedical Research & Applications” (BioBrillouin), will establish a collaborative network of leading researchers and instrument developers working in the field of Brillouin Light Scattering Spectroscopy (BLSS) applied to the life sciences and health related problems. BLSS uses visible or infrared light from a laser source(s) to probe the mechanics of a material through light scattering from thermally induced acoustic modes, or phonons. It gives access to the viscoelasticity and structure of matter in a nondestructive contactless way. When coupled to optical (confocal) microscopy, it has proven to be particularly well suited for biomedical applications. Though an established tool in condensed matter physics, only more recently has BLSS seen promising applications in the life sciences and medical diagnostics. This can largely be attributed to advances in instrument (spectrometer) design coupled with increasing interest in the biomechanics of cells and tissues and their relation to disease, underlying genetics and biochemistry. Unlike other mechanical and rheological measurement techniques, BLSS probes mechanical properties in the GHz frequency range, and thus offers a new ‘window’ for the investigation of microscopic scale biomechanical information. There are now a significant and increasing number of researchers actively working in BLSS for biomedical research in Europe. It is the aim of this COST action to bring together, for the first time, the diverse community working in the field, which includes instrument developers, physicists, chemists, biologists and clinicians, with the core aim to stimulate collaboration, promote technological advancement and pave the way towards routine life science research and clinical applications.

VBCF Newsletter Archive

2016

October

FEM tech Praktika for Female Students 2016

Funded by: BMVIT, via FFG

Duration: 1 – 6 months

Programme summary:

FEMtech fellowships for female students aims at initiating their career in the field of life sciences and technology (research, technology and development). The students get overview of the professional work in a company or at a research organization and get the first personal experience with research & developmental activities.

For the overview of the FEMtech fellowships 2016 see the table below:

Project acronyme

Student

Core Facility

Supervisor

Duration (months)

Funding (EUR)

KryoKonDrEi

Katharina Keuenhof

Electron Microscopy

Thomas Heuser

6

8480

Cancer Metabolomics

Anna Schoeberl

Metabolomics

Thomas Koecher

6

8480

Medical Brillouin

Franziska Gantner

Advanced Microscopy

Kareem Elsayad

2

3040

MRI of glioblastoma

Raphaela Hoefl

Preclinical Imgaging

Jelena Zinnanti

6

8480

MRI of glioblastoma

Cornelia Granl

Preclinical Imgaging

Lydia Zopf

6

8480

Data analysis

Alicia Serrano Drozdowskyj

Bioinformatics & Scientific Computing

Attila Gyenesei

3

4400

LSFM Internship

Angela Koffler

Advanced Microscopy

Edmundo Sanchez

6

8480

BEVS Optimization

Sarah Meitz

Protein Technologies

Peggy Stolt-Bergner

5

7120

Protein Tracking

Barbara Wolmuth

Strategic Information Management

Thomas Micheler

6

8480

HT plant phenotyping

Stefanie Koemeda

Plant Sciences

Jakub Jez

6

8480

RNAi line genotyping

Anna Pap

Vienna Drosophila Resource Center

Lisa Meadows

6

8480

Mausverhaltenstests

Bettina Sajtos

Preclinical Phenotyping

Sylvia Badurek

3

4400

preclin. phenotyping

Lejla Mastalic

Preclinical Phenotyping

Sylvia Badurek

6

4400

Total

 

 

 

64

91200

 

 

 

Creating synergies between research infrastructures to stimulate innovation in the cross-border region

Contact: Lada Fialova, Grant Manager, +43 1 796 2324 7013

Duration: 01. 09. 2016 – 31. 08. 2019

Partners: VBCF, ISTA Austria, CEITEC Masaryk University, Czech Republic, CEITEC Brno University of Technology, Czech Republic, Faculty Hospital of St. Anne, Czech Republic

Funded by: ERDF (European Regional Development Fund)

Total project costs: 1 495 000 EUR

Project summary:

Life sciences and technology rely increasingly on support from research infrastructures with specialized equipment and highly-skilled experts, and this trend is increasing and inevitable. The project contributes to the joint challenge of the cross-border region “Research and innovation” through creation of new synergies to increase institutional capacities.

The focus of the project will be on exploiting the potential of synergistic collaborations of the cross-border research infrastructures (RI) on the technology and management levels. The results of these collaborations will increase the quality and range of provided RI services, development of new applications and devices, and expand access to RIs to users throughout the cross-border region. The project will coherently contribute to development of the regional research and bio- and nanotech sector through innovation of RI by the offering of top innovative services, which will increase the region’s competitiveness in research. 

The two most prominent centers operating biomedical and technology RI in the AT – CZ cross-border region are Vienna Biocenter Core Facilities, GmbH in Vienna (VBCF) and Central European Institute of Technology in Brno (CEITEC). We have analysed instrumentation and expertises of the matching RIs and identified major obstacles and opportunities specific for these cross-border region RIs that need to be tackled and exploited, respectively, to boost the quality of research and services performed. The primary target groups will be researchers, RI operators, and biotech and nanotech companies.  The main outputs will be:

  • Improved knowledge on managing RI and expertise in providing cutting-edge services
  • Innovated research devices and services through joint use of cross-border complementary equipment
  • Enabled access of RI for external users from CZ-AT programme region
  • Increased involvement in the use of the RI by users coming from less-urbanised areas  

These outputs will be reached through RI staff exchange and trainings, innovative joint research projects taking advantage of complementary cross-border expertises, and workshops and an open access program to promote these services. These actions could not take place without cross-border cooperation, as they rely on infrastructure and expertise at each site that cannot be replicated at the other. This collaboration represents a unique opportunity to create a competitive advantage in the cross-border region. By taking other partners on board, namely FNUSA-ICRC and IST Austria we want to extend the close cooperation between VBCF and CEITEC to these institutes as well.

Open positions at partner institutions

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